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"Come Live With Me", written by André Previn, was inspired by the Christopher Marlowe poem of the same name.

Judy Garland complained about the press writing about her behavior on this film. She said: "The studio hadn't even built the set yet, and the tabloids had me walking off it".

Judy Garland kept her costume when she was fired from the film, and proceeded to wear the sequined pantsuit while performing in concerts around the world.

Judy Garland was originally cast in the main supporting role of Helen Lawson. The studio provided her with a pool table in her dressing room at her request. Eventually she was fired from the film because of her drinking and behavior and was replaced by Susan Hayward. Other actors considered as replacements were Tammy Grimes and Bette Davis. Reportedly Garland and Ethel Merman inspired the Lawson character.

Judy Garland was originally screen-tested and signed to play the main supporting role of Helen Lawson. The studio even provided her with a pool table in her dressing room at her request. Eventually she backed out of the film and was ultimately replaced by Susan Hayward. She kept her costume when she walked off the film, and proceeded to wear the sequined pantsuit while performing in concerts around the world. The character of Neely O'Hara in the film was partially based on her own history (with pills, alcohol, and failed marriages). Sadly, it was Garland's real-life pill addiction that contributed to her leaving this film.



Judy Garland's pre-recording of the song "I'll Plant My Own Tree" still survives today, as do her wardrobe tests.

Lucille Ball was originally considered for role of Helen Lawson, which went to _Susan Hayward (I)_ after Judy Garland left production.

Raquel Welch screen-tested for the role of Jennifer North. When she was then offered it she turned it down and was suspended by 20th Century-Fox as a result. Sharon Tate eventually took the part.

Barbara Parkins originally tested for the role of Neely O'Hara before she was cast as Anne Welles.

Marlo Thomas was also considered for the role of Anne Welles.

Dionne Warwick was under contract to a different record label than 20th so the theme on the soundtrack album was sung by Dory Previn, who also wrote the lyrics. Margaret Whiting dubbed Susan Hayward but she was also under contract to a different label, so veteran voice double Eileen Wilson sings "I'll Plant My Own Tree" on the soundtrack album.

Dionne Warwick's Scepter rerecording of the movie theme would peak at number two on "Billboard"'s Hot 100 chart in February 1968. Dionne's 45 held the second slot for a month. Without Miss Warwick's presence, the soundtrack album, released by 20th Century Fox Records, entered the "Billboard" pop albums list in January 1968, and the LP then climbed to eighth place.

An original, unused theme song was written by novelist Jacqueline Susann and Bob Gaudio of The Four Seasons.

Film debut of Richard Dreyfuss.

For the three lead roles the following actors were considered: Petula Clark, Raquel Welch, Ann-Margret, Candice Bergen, and Jill Ireland. In the end Sharon Tate, Patty Duke and Barbara Parkins played the roles.

Her last album release for United Artists Records, "Patty Duke Sings Songs From Valley of the Dolls and Other Selections" failed to rack up robust sales, and the LP would go out of print after just one year. Gene Kelly, writing the liner notes, extolled, "Of course, Patty is an exciting singer, but precisely because her voice is excited and emotional and full of action."

One of the films included in "The Fifty Worst Films of All Time (and how they got that way)" by Harry Medved and Randy Lowell.

Some ads for the film featured photos of the female leads, along with taglines about each individual character and her pill color of preference ("This is so-and-so; she took the red pills.") Unfortunately, the ad department hadn't paid much attention to the movie because same approach was taken with Susan Hayward's character Helen Lawson - the only lead female character who didn't take pills and was in fact quite vocal in her dislike of recreational pill-popping.

Stephen M. Moser of the Austin Chronicle wrote about this film: "The definitive camp classic ... "Valley of the Dolls" is a great movie in the very same way that Showgirls is a great movie. Rent it and howl!"

The book's author, Jacqueline Susann has a cameo as one of the reporters.

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